British Air Force Typhoon FGR4s have conducted a mission with France's air force in a joint strike targeting an hidden munitions depot in Syrian territory employed by the IS group, as stated by the UK's MoD.
The location, located using reconnaissance, was believed to be containing munitions and bombs, the announcement noted, and was located in mountainous terrain just north of the historic site of Palmyra in Syria's central region.
"Our aircraft utilized Paveway IV guided bombs to hit a series of approach shafts providing entry to the depot... early reports indicate the strike was effective," the ministry announced.
There was no sign of any harm to civilians in the attack on Saturday evening and all the aircraft made a safe return, the ministry further stated.
The Typhoon FGR4s were backed up by a Voyager aerial refuelling aircraft.
IS - referred to as ISIS - imposed jihadist rule over parts of Iraq and Syria prior to its 2019 collapse.
"This action demonstrates British leadership, and resolve to work closely with our partners, to eradicate any revival of IS and their dangerous and violent ideologies in the region," the British Defence Secretary John Healey remarked.
British military aircraft have conducted surveillance missions over Syrian airspace to "deter any attempted resurgence" of the group following its routing at the climactic battle in Baghuz in 2019, the ministry said.
"I must thank every member of British forces participating in this strike for their expertise and their valour," the Defence Secretary said. "They were among thousands of British personnel deployed over Christmas and New Year. This action, to remove terrorist threats who pose a risk to our safety, shows how British military are prepared to act, all year round, ensuring Britain's security domestically and strong abroad."
Last December, the United States armed forces conducted what it called a "massive strike" on Islamic State objectives in the country, subsequent to an attack killed two American soldiers and a local interpreter in Palmyra.
The U.N. reports Islamic State still maintains an estimated 5,000 to 7,000 fighters in Syria and Iraq.